Homer Boushey, MD, Chief of Asthma Clinical Research Center (ACRC) and Division of Allergy & Immunology, has been studying the causes and treatments of asthma for over 25 years with training at UCSF, Harvard, Oxford and the University of Paris.  He is the Principal Investigator for National Institutes of Health (NIH) studies on asthma and served on the National Asthma Expert Panel of the NIH.  This Committee developed national guidelines for the diagnosis and treatment of asthma.

Recent Publications

Wechsler ME, Lehman E, Lazarus SC, Lemanske RF Jr, Boushey HA, Deykin A, Fahy JV, Sorkness CA, Chinchilli VM, Craig TJ, DiMango E, Kraft M, Leone F, Martin RJ, Peters SP, Szefler SJ, Liu W, Israel E. “beta-Adrenergic receptor polymorphisms and response to salmeterol” Am J Respir Crit Care Med. 2006 Mar 1;173(5):519-26.

Chen Y, Hamati E, Lee W-M, Wachi S, Schnurr D, Yagi S,  Dolganov G,Boushey HA, and Wu R. “Transcriptional Profiling of Gene Expression in Rhinovirus Infected Human Primary Airway Epithelial Cells: Elevation of Innate Defense Molecules through both dsRNA and Interferon Dependent Pathways” Am J Resp Cell Mol Biol. 2006 Feb;34(2):192-203.

Martin Richard J, Szetfler SJ, King TS, Kraft M, Boushey HA, Chichilli VM, Craig TJ, DiMango,EA, Deykin A, Fahy JV, Israel E, Lazarus LC, Lemanske RF, Leone FT, Pesola R, Peters SP, Sorkness CA, Szwejbka LA, Wechsler ME.  “The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) Trial” J Allergy Clin Immunol 2007 119(1):73-80.

Lazarus, SC, Chinchilli VM, Rollings NJ, Boushey HA, Cherniack R, Craig TJ, Deykin A, Dimango E, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lemanske Jr RF, Leone F, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ.  “Smoking Affects Response to Inhaled Corticosteroids or Leukotriene Receptor Antagonists in”  Am J Respir Crit Care Med 2007.

Deykin A, Wechsler ME, Boushey HA, Chinchilli VM, Kunselman SJ, Craig TJ, DiMango E, Fahy JV, Kraft M, Leone F, Laarus SC, Lemanske RF Jr, Martin RJ, Pesola GR, Peter SP, Sorkness CA, Szefler SJ, Israel E.  “Combination Therapy with Long-Acting beta-Agonist and a Leukotriene Antagonist in Moderate Asthma” Am J Respir Crit Care Med 2007;175(3):228-34.

Amy Kistler, Pedro C. Avila, Silvi Rouskin1, David Wang, Theresa Ward4, Shigeo Yagi, David Schnurr5 Don Ganem, Joe DeRisi, and Homer A. Boushey “Pan-viral screening of respiratory tract infections in asthmatic and non-asthmatic adults reveals unexpected coronavirus and human rhinovirus diversity.” Journal of Infectious Disease in press 2007.

Kistler A, Webster D, Rouskin S, Magrini V, Credle J, Schnurr D, Boushey HA, Mardis E, Li H, DeRisi JL. “Genome-wide diversity and selective pressure in the human rhinovirus.” Virology Journal, in press 2007.

Woodruff PG, Boushey HA, Dolganov GM, Baker CS, Yang YH, Donnelly S, Ellwanger A, Sidhu S, Dao-Ick TP, Pantoja C, Erle DJ, Yamamoto KR, Fahy JV.  “Genome-Wide Profiling Identifies Epithelial Cell Genes Associated with Asthma and with Treatment Response to Corticosteroids” PNAS (submitted 2007).

Yawn BP, Enright PL, Lemanske RF, Israel E, Pace W, Wollan P, Boushey HA. “Spirometry can be done in family physicians’ offices and alters clinical decisions in management of asthma and COPD.”  Chest 2007 June 5; [Epub ahead of print]

Yoo J, Tcheurekdjian H, Lynch SV, Cabana M, Boushey HA. “Microbial manipulation of immune function for asthma prevention: inferences from clinical trials.”  Proc Am Thorac Soc. 2007 July;4(3): 277-82

Boushey HA, Enright P. “Spirometry enhances identification of high risk patients with asthma.”  Chest 2007 (in press)

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Last Update:4/08/08